2012年2月27日星期一

Use of automatic blood analyzer to detect blood sugar technology research (3)

  IV.Dynamic blood glucose monitoring technology
  Because of biochemical analysis and fast blood cells analyzer and this minimally invasive technique can't or continuous dynamic detection of patients with glucose in the blood and can't get closer to the truth so, dynamic blood glucose monitoring system (CGMS) came into being dynamic spectrometry can eliminate individual differences and measuring conditions on the influence of the spectral measurement.


   Studies have think that, as a result of the pulse of the phenomenon, blood vessels in blood flow to a periodic change, blood is not transparent liquid, the light in the blood, penetrating than in the organization through small a few times, so the change may cause the pulse of near infrared spectral absorbency change, so through the dynamic spectrum record artery to maximum and filled with the arterial constriction of the most hours to spectrophotometry value, can remove the individual differences and measuring conditions on the influence of the spectral measurements, correction model prediction ability, improve the precision of the spectral measurement MiniMed company production of the United States CGMS already in June 1999, the FDA approved for listing. 


    CGMS is a minimally invasive blood glucose monitoring system, by detecting subcutaneous tissue of the liquid glucose concentration between and reflect the blood sugar level, it will continuously monitoring patient 1 day at each hour of the blood glucose levels, this instrument is only the size of a mobile phone, with microcomputer chip, there is a slight hose connection instruments and detection head, detection head into the subcutaneous tissue every 10 seconds from detector instrument to an electrical signal changes reflect blood sugar, the electric signals of every 5 minutes average conversion to blood sugar leels storage up every day can record store 288 blood sugar value the instrument and can also record and storage dine sports events such as drug use. 


    CGMS to continuous monitoring three days (72 hours) the dynamic change of blood sugar, and then the data can be downloaded to the ordinary computers, provide to the doctor diagnose evidence however, CGMS and non-invasive detection techniques of GWG2B device, accuracy also there are some problems, mainly in induced insulin hypoglycemia, these devices monitor blood glucose is not high credibility, therefore, the food and drug administration suggest not only the material and change the treatment, must first use standard of blood glucose meter checked.


    To sum up, and the technology and noninvasive technique each have advantages and disadvantages, in a long stage, two kinds of technology will complement each other, common development, but diabetes diagnosis must through

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